Original Papers

Preprints

1. A Persistent Ni(0)–Pentalene Complex with High Fluxionality: Does Stronger Antiaromaticity Promote Metal–Ligand Interactions?
R. Kuwata, T. Imanishi, S. Hasegawa, Z. Wang, J. Usuba, K. Yasui, M. U. G. Khan, J. I. Wu, Y. Uetake,* A. Fukazawa*
ChemRxiv (posted on 11 November 2025, Version 2)
DOI: 10.26434/chemrxiv-2025-l8c87-v2

Peer-Reviewed Papers

64. 1,6-Disila[4.4.4]propellane Revisited – Part 1: Improved Synthesis by a Mechanistically Logical Fluorosilane Route and Its Structural Aspects Including Linear Stacking along the Si–Si Bond in the Crystalline State
S. Kobayashi, T. Sasamori,* Y. Nakajima, Y. Minami, K. Iizuka, T. Saeki, A. Toshimitsu, H. Tsuji, S. Yamaguchi, A. Fukazawa, T. Kushida, D. Hashizume, K. Tamao*
Bull. Chem. Soc. Jpn. 2026, 99, uoaf119.
DOI: 10.1093/bulcsj/uoaf119

53. Negative Fluorescence Anisotropy of Phosphole Oxide-Based Dyes in Nematic Liquid Crystals
T. Ohzono,* T. Yatabe, C. Wang, A. Fukazawa, S. Yamaguchi Communications Chemistry, 2018, 1, Article number 52.
DOI: 10.1038/s42004-018-0055-6

52. End-Capping π-Conjugated Systems with Medium-Sized Sulfur-Containing Rings: A Route Towards Solution-Processable Air-Stable Semiconductors
A. Fukazawa,* Y. Toda, M. Hayakawa, A. Sekioka, H. Ishii, T. Okamoto, J. Takeya, Y. Hijikata, S. Yamaguchi*
Chem. Eur. J. 2018, 24, 11503–11510.
DOI: 10.1002/chem.201802656
Highlighted in SYNFACTS

51. Water-Soluble Phospholo[3,2-b]phosphole P,P’-Dioxide-Based Fluorescent Dyes with High Photostability
C. Wang, A. Fukazawa,* Y. Tanabe, N. Inai, D. Yokogawa, S. Yamaguchi*
Chem. Asian J. 2018, 13, 1616–1624.
DOI: 10.1002/asia.201800533

50. Near Infrared Two-Photon-Excited and -Emissive Dyes Based on a Strapped Excited-State Intramolecular Proton-Transfer (ESIPT) Scaffold
N. Suzuki, K. Suda, D. Yokogawa,* H. Kitoh-Nishioka, S. Irle, A. Ando, L. M. G. Abegão, K. Kamada,* A. Fukazawa, S. Yamaguchi*
Chem. Sci. 2018, 9, 2666–2673.
DOI: 10.1039/C8SC00066B
Highlighted in an Inside Back Cover

49. Uncovering Different States of Topological Defects in Schlieren Textures of a Nematic Liquid Crystal
T. Ohzono,* K. Katoh, C. Wang, A. Fukazawa, S. Yamaguchi, J.-i. Fukuda*
Sci. Rep. 2017, 7, 16814.
DOI: 10.1038/s41598-017-16967-1
Ranked in the top 100 read physics papers for Scientific Reports in 2017 (among more than 3000 papers)

48. Photochemical Intramolecular C–H Addition of Dimesityl(hetero)arylboranes via a [1,6]-Sigmatropic Rearrangement
N. Ando, A. Fukazawa, T. Kushida, Y. Shiota, S. Itoyama, K. Yoshizawa,* Y. Matsui, Y. Kuramoto, H. Ikeda,* S. Yamaguchi*
Angew. Chem. Int. Ed. 2017, 56, 12210–12214.
DOI: 10.1002/anie.201706929

47. Super-Photostable Phosphole-Based Dye for Multiple-Acquisition STED Imaging
C. Wang, M. Taki,* Y. Sato,* A. Fukazawa,* T. Higashiyama, S. Yamaguchi*
J. Am. Chem. Soc. 2017, 139, 10374–10381.
DOI: 10.1021/jacs.7b04418
Press release (Nagoya University)
Highlighted in web (日本の研究.com, Optronics Online)

46. Synthesis of Seminaphtho-Phospha-Fluorescein Dyes Based on Consecutive Arylation of Aryldichlorophosphines
A. Fukazawa,* J. Usuba, R. A. Adler, S. Yamaguchi*
Chem. Commun. 2017, 53, 8565–8568.
DOI: 10.1039/C7CC04323F

45. Structures and Physical Properties of Chemically Reduced Diindenosiloles and Their π-Extended Derivatives
R. Takano, R. Shintani,* A. Fukazawa, S. Yamaguchi,* K. Nakabayashi, S.-i. Ohkoshi, K. Nozaki*
Organometallics 2017, 36, 2646–2653.
DOI: 10.1021/acs.organomet.7b00260

44. A New Infrared Dye that Undergoes Multiple Interconversions through Acid-Base Equilibria and Reversible Redox Processes
K. Asai, A. Fukazawa,* S. Yamaguchi*
Angew. Chem. Int. Ed. 2017, 56, 6848–6852.
DOI: 10.1002/anie.201702140

43. Tuning the Photophysical Properties of Photostable Benzo[b]phosphole P-Oxide-Based Fluorophores
R. A. Adler, C. Wang, A. Fukazawa,* S. Yamaguchi*
Inorg. Chem. 2017, 56, 8718–8725.
DOI: 10.1021/acs.inorgchem.7b00658

42. Synthesis and Physical Properties of Strained Doubly Phosphorus-Bridged Biaryls and Viologens
T. W. Greulich, E. Yamaguchi, C. Doerenkamp, C. G. Daniliuc, A. Fukazawa, H. Eckert,* S. Yamaguchi,* A. Studer*
Chem. Eur. J. 2017, 23, 6029–6033.
DOI: 10.1002/chem.201605272

41. Facile Synthesis of Polycyclic Pentalenes with Enhanced Hückel Antiaromaticity
H. Oshima, A. Fukazawa,* S. Yamaguchi*
Angew. Chem. Int. Ed. 2017, 56, 3270–3274.
DOI: 10.1002/anie.201611344
Highlighted in a Back Cover
Highlighted in SYNFACTS

40. Stable Red-Emissive Cationic Dithienotropylium Dyes
K. Asai, A. Fukazawa,* S. Yamaguchi*
Chem. Eur. J. 2016, 22, 17571–17575.
DOI: 10.1002/chem.201604509

39. A Macrocyclic Fluorophore Dimer with Flexible Linkers: Bright Excimer Emission with Long Fluorescence Lifetime
H. Osaki, C.-M. Chou, M. Taki,* K. Welke, D. Yokogawa, S. Irle,* Y. Sato, T. Higashiyama, S. Saito, A. Fukazawa, S. Yamaguchi*
Angew. Chem. Int. Ed. 2016, 55, 7131–7315.
DOI: 10.1002/anie.201602239
Highlighted as a Hot Paper

38. A Biphenyl Containing Two Electron-Donating and Two Electron-Accepting Moieties: A Rigid and Small Donor–Acceptor–Donor Ladder System
T. W. Greulich, N. Suzuki, C. G. Daniliuc, A. Fukazawa, E. Yamaguchi, A. Studer,* S. Yamaguchi*
Chem. Commun. 2016, 52, 2374–2377.
DOI: 10.1039/C5CC03063C
Highlighted in SYNFACTS

37. Phospha-fluorescein: A Red-Emissive Fluorescein Analogue with High Photobleaching Resistance
A. Fukazawa,* S. Suda, M. Taki,* E. Yamaguchi, M. Grzybowski, Y. Sato, T. Higashiyama, S. Yamaguchi*
Chem. Commun. 2016, 52, 1120–1123.
DOI: 10.1039/C5CC09345G
Highlighted as a Cover Picture

36. A Phosphole Oxide Based Fluorescence Dye with Exceptional Resistance to Photobleaching: A Practical Tool for Continuous Imaging in STED Microscopy
C. Wang, A. Fukazawa,* M. Taki,* Y. Sato, T. Higashiyama,* S. Yamaguchi*
Angew. Chem. Int. Ed. 2015, 54, 15213–15217.
DOI: 10.1002/anie.201507939
Press release (Nagoya University)
Highlighted in a newspaper (日経産業新聞) and websites (日本の研究.com, Alpha Galileo JP, EurekAlert!JP, Optronics Online, BioOptics, asia RESEACH NEWS)
超耐光性蛍光色素として市販化（2017年9月発売, 商品名 C-Naphox-TEG, 東京化成工業株式会社）

35. A Benzophosphole P-Oxide with an Electron-Donating Group at 3-Position: Enhanced Fluorescence in Polar Solvents
E. Yamaguchi, A. Fukazawa,* Y. Kosaka, D. Yokogawa, S. Irle,* S. Yamaguchi*
Bull. Chem. Soc. Jpn. 2015, 88, 1545–1552.
DOI: 10.1246/bcsj.20150238
Selected Paper in Issue 11, 2015

34. A Red-emitting Ratiometric Fluorescent Probe Based on a Benzophosphole P-oxide Scaffold for the Detection of Intracellular Sodium Ions
M. Taki,* H. Ogasawara, H. Osaki, A. Fukazawa, Y. Sato, K. Ogasawara, T. Higashiyama, S. Yamaguchi*
Chem. Commun. 2015, 51, 11880–11883.
DOI: 10.1039/C5CC03547C

33. A Nonaromatic Thiophene-fused Heptalene and Its Aromatic Dianion
H. Oshima, A. Fukazawa,* T. Sasamori, S. Yamaguchi*
Angew. Chem. Int. Ed. 2015, 54, 7636–7639.
DOI: 10.1002/anie.201501790

32. A Cyclic Octithiophene Containing β,β’-Linkages
K. Asai, A. Fukazawa,* S. Yamaguchi*
Chem. Commun. 2015, 51, 6096–6099.
DOI: 10.1039/C5CC00570A

31. Environment-Sensitive Fluorescent Probe: A Benzophosphole Oxide with an Electron-Donating Substituent
E. Yamaguchi, C. Wang, A. Fukazawa,* M. Taki, Y. Sato, T. Sasaki, M. Ueda, N. Sasaki, T. Higashiyama,* S. Yamaguchi*
Angew. Chem. Int. Ed. 2015, 54, 4539–4543.
DOI: 10.1002/anie.201500229
Highlighted in an Inside Cover
高感度な脂肪滴ライブセルイメージング色素として市販化（2016年7月発売, 商品名LipiDye, フナコシ株式会社）

30. A Strap Strategy for Construction of an Excited-State Intramolecular Proton Transfer (ESIPT) System with Dual Fluorescence
N. Suzuki, A. Fukazawa, K. Nagura, S. Saito, H. Kitoh-Nishioka, D. Yokogawa, S. Irle,* S. Yamaguchi*
Angew. Chem. Int. Ed. 2014, 53, 8231–8235.
DOI: 10.1002/anie.201404867

29. Dearomatization-Induced Transannular Cyclization: Synthesis of Electron-Accepting Thiophene-S,S-Dioxide-Fused Biphenylene
A. Fukazawa,* H. Oshima, S. Shimizu, N. Kobayashi, S. Yamaguchi*
J. Am. Chem. Soc. 2014, 136, 8738–8745.
DOI: 10.1021/ja503499n
Highlighted in SYNFACTS

28. The B(C₆F₅)₃Boron Lewis Acid Route to Arene-Annulated Pentalenes
C. Chen, M. Harhausen, A. Fukazawa, S. Yamaguchi,* R. Fröhlich, C. G. Daniliuc, J. L. Petersen, G. Kehr, G. Erker*
Chem. Asian J. 2014, 9, 1671–1681.
DOI: 10.1002/asia.201400096

27. Synthesis of Pyridine N-Oxide-BF₂CF₃Complexes and Their Fluorescence Properties
T. Nishida, A. Fukazawa, E. Yamaguchi, H. Oshima, S. Yamaguchi, M. Kanai,* Y. Kuninobu*
Chem. Asian J. 2014, 9, 1026–1030.
DOI: 10.1002/asia.201301688

26. Hydroxyphenyl-Substituted Benzophosphole Oxides: Impact of the Intramolecular Hydrogen Bond on the Fluorescence Properties
A. Fukazawa,* H. Osaki, S. Yamaguchi*
Asian J. Org. Chem. 2014, 3, 122–127.
DOI: 10.1002/ajoc.201300227
Highlighted as a Cover Picture
Highlighted in ChemistryViews (Wiley-VCH)

25. Diarylated Bi(thieno[2,3-c]thiophene)s: A Ring-fusing Strategy for Controlling the Molecular Alignment of Oligoarenes
A. Fukazawa,* D. Kishi, Y. Tanaka, S. Seki, S. Yamaguchi*
Angew. Chem. Int. Ed. 2013, 52, 12091–12095.
DOI: 10.1002/anie.201306323

24. Photochemical Double 5-exo–dig Cyclization of Alkenyl-substituted Dithienylacetylenes: Efficient Synthesis of Diarylated Dithienofulvalenes
A. Fukazawa,* T. Karasawa, H. Zhang, K. Minemura, C. Camacho, J. Wang, S. Irle,* S. Yamaguchi*
Angew. Chem. Int. Ed. 2013, 52, 10519–10523.
DOI: 10.1002/anie.201303738

23. Dibenzopentalenes by B(C₆F₅)₃Induced Cyclization Reactions of 1,2-Bis(phenylethynyl)benzenes
C. Chen, M. Harhausen, R. Liedtke, K. Bussmann, A. Fukazawa, S. Yamaguchi,* J. L. Petersen, C. G. Daniliuc, R. Fröhlich, G. Kehr, G. Erker*
Angew. Chem. Int. Ed. 2013, 52, 5992–5996.
DOI: 10.1002/anie.201300871
Highlighted in SYNFACTS

22. S-Pechmann Dye: A Thiolactone-Containing Organic Dye with Pronounced Electron-Accepting Character and Its Solid-State Photophysical Properties
A. Fukazawa,* M. Adachi, K. Nakakura, S. Saito, S. Yamaguchi*
Chem. Commun. 2013, 49, 7117–7119.
DOI: 10.1039/C3CC41007B
Highlighted in a Back Cover

21. Thiophene-Fused Bisdehydro[12]annulene That Undergoes Transannular Alkyne Cycloaddition by Either Light or Heat
A. Fukazawa,* H. Oshima, Y. Shiota, S. Takahashi, K. Yoshizawa,* S. Yamaguchi*
J. Am. Chem. Soc. 2013, 135, 1731–1734.
DOI: 10.1021/ja3126849
Highlighted in SYNFACTS

20. Sequential Electrophilic and Photochemical Cyclizations from Bis(bithienyl)acetylene to a Tetrathienonaphthalene Core
C. Dou, S. Saito, L. Gao, N. Matsumoto, T. Karasawa, H. Zhang, A. Fukazawa, S. Yamaguchi*
Org. Lett. 2013, 15, 80–83.
DOI: 10.1021/ol303107y

19. Reaction of Pentaarylboroles with Carbon Monoxide: An Isolable Organoboron Carbonyl Complex
A. Fukazawa, J. L. Dutton, C. Fan, L. G. Mercier, A. Y. Houghton, Q. Wu, W. E. Piers,* M. Parvez
Chem. Sci. 2012, 3, 1814–1818.
DOI: 10.1039/C2SC20336G

18. Electron-Donating Tetrathienyl-Substituted Borole
T. Araki, A. Fukazawa, S. Yamaguchi*
Angew. Chem. Int. Ed. 2012, 51, 5484–5487.
DOI: 10.1002/anie.201201156

17. Combined Experimental and Theoretical Studies on the Photophysical Properties of Cycloparaphenylenes
Y. Segawa, A. Fukazawa, S. Matsuura, H. Omachi, S. Yamaguchi,* S. Irle,* K. Itami*
Org. Biomol. Chem. 2012, 10, 5979–5984.
DOI: 10.1039/C2OB25199J

16. Synthesis and Photophysical Properties of Aryl Substituted 2-Borylbenzaldimines and their Extended π-Conjugated Congeners
B. Neue, R. Fröhlich, B. Wibbeling, A. Fukazawa, A. Wakamiya, S. Yamaguchi,* E.-U. Würthwein*
J. Org. Chem. 2012, 77, 2176–2184.
DOI: 10.1021/jo202212s

15. Bis(phosphoryl)-bridged Biphenyls by Radical Phosphanylaion: Synthesis, Photophysical and Electrochemical Properties
A. Bruch, A. Fukazawa, E. Yamaguchi, S. Yamaguchi,* A. Studer*
Angew. Chem. Int. Ed. 2011, 50, 12094–12098.
DOI: 10.1002/anie.201104114

14. Synthesis and Structures of a Series of Bulky “Rind-Br” Based on a Rigid Fused-Ring s-Hydrindacene Skeleton
T. Matsuo,* K. Suzuki, T. Fukawa, B. Li, M. Ito, Y. Shoji, T. Otani, L. Li, M. Kobayashi, M. Hachiya, Y. Tahara, D. Hashizume, T. Fukunaga, A. Fukazawa, Y. Li, H. Tsuji, K. Tamao*
Bull. Chem. Soc. Jpn. 2011, 84, 1178–1191.
DOI: 10.1246/bcsj.20110090
Selected as the BCSJ Award Article in Nov. 2011 & Cover Picture

13. Zwitterionic Ladder Stilbenes with Phosphonium and Borate-Bridges: Intramolecular Cascade Cyclization and Structure-Photophysical Properties Relationship
A. Fukazawa,* E. Yamaguchi, E. Ito, H. Yamada, J. Wang, S. Irle,* S. Yamaguchi*
Organometallics 2011, 30, 3870–3879.
DOI: 10.1021/om200453w

12. Phosphine Sulfides as an Anchor Unit for Single Molecule Junction
A. Fukazawa,* M. Kiguchi,* S. Tange, Y. Ichihashi, Q. Zhao, T. Takahashi, T. Konishi, K. Murakoshi, Y. Tsuji, A. Staykov, K. Yoshizawa,* S. Yamaguchi*
Chem. Lett. 2011, 40, 174–176.
DOI: 10.1246/cl.2011.174
Selected as Editor’s Choice

11. Intense Fluorescence of 1-Aryl-2,3,4,5-tetraphenylphosphole Oxides in the Crystalline State
A. Fukazawa, Y. Ichihashi, S. Yamaguchi*
New J. Chem. 2010,34, 1537–1540. (Themed Issue: Main Group Chemistry)
DOI: 10.1039/c0nj00155d
Highlighted as an Inside Front Cover

10. Thiophene-Fused Phospholo[3,2-b]phospholes and Their Dichalcogenides: Synthesis and Structure-Photophysical Properties Relationships
A. Fukazawa, T.-a. Murai, L. Li, Y. Chen, S. Yamaguchi*
C. R. Chimie 2010, 13, 1082–1090. (Special issue: Phosphorus Chemistry Today)
DOI: 10.1016/j.crci.2010.04.021

9. Zwitterionic Ladder Bis(arylethenyl)benzenes with Large Two-Photon Absorption Cross Sections
A. Fukazawa, H. Yamada, Y. Sasaki, S. Akiyama, S. Yamaguchi*
Chem. Asian J. 2010, 5, 466–469.
DOI: 10.1002/asia.200900517
Most accessed articles in 01/2010

8. Benzo[b]phosphole-Containing π-Electron Systems: Synthesis Based on an Intramolecular trans-Halophosphanylation and Some Insights into Their Properties
A. Fukazawa, Y. Ichihashi, Y. Kosaka, S. Yamaguchi*
Chem. Asian J. 2009, 4, 1729–1740.
DOI: 10.1002/asia.200900303
Most accessed articles in 10/2009

7. Structural Modification of Silicon-Bridged Ladder Stilbene Oligomers and Distyrylbenzenes
H. Yamada, C. Xu, A. Fukazawa, A. Wakamiya, S. Yamaguchi*
Macro. Chem. Phys. 2009,210, 904–916.
DOI: 10.1002/macp.200900037

6. Phosphonium and Borate-Bridged Zwitterionic Ladder Stilbene and Its Extended Analogues
A. Fukazawa, H. Yamada, S. Yamaguchi*
Angew. Chem. Int. Ed. 2008, 47, 5582–5585.
DOI: 10.1002/anie.200801834
Highlighted in SYNFACTS

5. Bis-Phosphoryl-Bridged Stilbenes Synthesized by an Intramolecular Cascade Cyclization
A. Fukazawa, M. Hara, T. Okamoto, E.-C. Son, C. Xu, K. Tamao, S. Yamaguchi*
Org. Lett. 2008, 10, 913–916.
DOI: 10.1021/ol7030608

4. Coplanar Oligo(p-phenylenedisilenylene)s Based on the Octaethyl-Substituted s-Hydrindacenyl Groups
A. Fukazawa, Y. Li, S. Yamaguchi, H. Tsuji,* K. Tamao*
J. Am. Chem. Soc. 2007, 129, 14164–14165.
DOI: 10.1021/ja0764207

3. Skeletal Rearrangement of a Bicyclic 1,3-Diphenyltrisilane during Acid-Induced Dephenylation Reactions
A. Fukazawa, H. Tsuji,* K. Tamao*
Silicon Chemistry 2007, 3, 157–163.
DOI: 10.1007/s11201-006-9022-7

2. all-anti-Octasilane: Conformation Control of Silicon Chains Using the Robust Bicyclic Trisilane as the Building Block
A. Fukazawa, H. Tsuji,* K. Tamao*
J. Am. Chem. Soc. 2006, 128, 6800–6801.
DOI: 10.1021/ja0616231

1. All-anti Pentasilane: Conformation Control of Oligosilanes Based on Bis(tetramethylene)-tethered Trisilane Unit
H. Tsuji, A. Fukazawa, S. Yamaguchi, A. Toshimitsu, K. Tamao*
Organometallics 2004, 23, 3375–3377.
DOI: 10.1021/om049695t

Reviews and Accounts

4. Phosphole P-Oxide-Containingp-Electron Materials: Synthesis and Applications in Fluorescence Imaging
S. Yamaguchi, A. Fukazawa, M. Taki
J. Syn. Org. Chem., Jpn. 2017, 75, 1179–1187.

3. 超耐光性蛍光色素が拓く蛍光バイオイメージング
佐藤良勝，Chenguang Wang，深澤愛子，多喜正泰，東山哲也，山口茂弘
Plant Morphology 2016, 28, 9–13.

2. Synthetic Study of Novel π-Electron Materials Containing Boron, Nitrogen, and Phosphorus as a Key Main Group Elements
S. Yamaguchi A. Fukazawa
J. Syn. Org. Chem., Jpn. 2011, 69, 661–670.

1. Ladder π-Conjugated Materials Containing Main Group Elements
A. Fukazawa, S. Yamaguchi
Chem. Asian J. 2009, 4, 1386–1400. 

Editorial Remarks and Miscellaneous Articles

Novel Aromatics: Official Special Issue of ISNA-18
A. Fukazawa, S. Toyota,* R. Tykwinski,* W. Wong, ChemPlusChem 2019, 84, 562–563. (Editorial)
DOI: 10.1002/cplu.201900232

Books & Book Chapters

フラーレンを超える分子をデザインし，創る
深澤愛子
有機化学イノベーション–ひらめきと直感をいかに呼び込むか (現代化学増刊47)，山本 尚 監修，東京化学同人 (2023).

機能性材料への応用
山口茂弘，深澤愛子
現代ケイ素化学–基礎から応用まで，吉良満夫，玉尾皓平編，化学同人 pp. 333-347 (2013)．

Commentaries

チオフェンの「適度な芳香族性」を鍵とするπ電子系のデザイン
深澤愛子
化学と工業 2013, 66, 1000–1001.

芳香環を使った分子のだまし絵– シクロビス[4]ヘリセンの合成
深澤愛子
化学 2012, 67, 63–64.

触媒の精密設計に基づく高速クロスカップリング反応の実現
深澤愛子
Organometallic News 2011, 57.

ホスフィンオキシドで単分子層ができた！
深澤愛子
化学 2008, 63, 67–68.

リンは窒素を超えられるか？—機能性分子を指向した有機リン化学の最近の動向
深澤愛子，山口茂弘
化学 2006, 61, 68–69.

Essays

研究者人生で最大の転機？この11年間の足跡
深澤愛子
化学と工業 2025, 78, 524–525.

コロナ禍における超ポジティブ思考
深澤愛子
化学と工業 2022, 75, 231. （「CGI サロン：この人，紹介」欄）